Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.41 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281731 | 0.74 | CTRC (0.39) | TSHRCYP2D6MEN1KMT2ACYP19A1 | |
| SCHEMBL28218138 | 0.71 | KMT2A (0.42) | ACHENOS3NOS2NOS1CYP2D6 | |
| SCHEMBL28218150 | 0.69 | CYP2D6 (0.41) | ACHENOS3NOS2NOS1CYP2D6 | |
| SCHEMBL840754 | 0.69 | NOS3 (0.47) | ACHENOS3NOS2NOS1TSHR | |
| SCHEMBL13178128 | 0.67 | CYP2D6 (0.39) | ACHENOS3NOS2NOS1CYP2D6 | |
| SCHEMBL29180076 | 0.67 | RAB9A (0.41) | ACHENOS3NOS2NOS1TSHR | |
| SCHEMBL28218106 | 0.67 | CYP2D6 (0.39) | ACHENOS3NOS2NOS1CYP2D6 | |
| SCHEMBL18973812 | 0.66 | CYP2D6 (0.38) | ACHENOS3NOS2NOS1CYP2D6 | |
| SCHEMBL5542657 | 0.65 | NOS3 (0.40) | NOS3NOS2NOS1BRD4MEN1 | |
| SCHEMBL10352987 | 0.65 | ANPEP (0.57) | ACHETSHRBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908753-A1 | NOVEL HETEROCYCLIDENE ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |