SCHEMBL4773926

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19581824	0.81	KMT2A (0.41)	PIM2KMT2AMEN1POLBMAPT
	SCHEMBL24766459	0.74	CYP1A2 (0.49)	KMT2AMEN1POLBMAPTCYP1A2
	SCHEMBL245740	0.74	KMT2A (0.49)	KMT2AMEN1POLBMAPTCYP1A2
	SCHEMBL5524143	0.74	ALDH1A1 (0.44)	PIM2KMT2AMEN1POLBMAPT
	SCHEMBL9885000	0.74	KMT2A (0.53)	KMT2AMEN1POLBMAPTCYP1A2
	SCHEMBL12186838	0.74	KMT2A (0.41)	PIM2KMT2AMEN1POLBMAPT
	SCHEMBL3089415	0.74	KMT2A (0.64)	PIM2KMT2AMEN1POLBMAPT
	SCHEMBL4763503	0.71	ALDH1A1 (0.48)	KMT2AMEN1MAPTHTTALDH1A1
	SCHEMBL15582906	0.71	KMT2A (0.42)	PIM2KMT2AMEN1POLBMAPT
	SCHEMBL20153720	0.70	PIK3CA (0.45)	PIM2POLBMAPTHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.