Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 8/20 | 0.32 |
| ▸ | DRD4 | P21917 | 6/20 | 0.32 |
| ▸ | DRD1 | P21728 | 5/20 | 0.32 |
| ▸ | DRD5 | P21918 | 5/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961007 | 0.78 | HTR2C (0.41) | DRD2HTR6DRD3HTR1D | |
| Hydrochloric Acid SCHEMBL3963008 | 0.77 | HTR2C (0.40) | DRD2HTR6DRD3HTR1D | |
| SCHEMBL3963797 | 0.69 | DRD2 (0.42) | DRD2DRD3HTR1D | |
| SCHEMBL7023211 | 0.69 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL16926997 | 0.67 | DRD2 (0.41) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL18015659 | 0.67 | DRD2 (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL5599422 | 0.66 | PTGS2 (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL31265222 | 0.66 | PTGS2 (0.43) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL17733199 | 0.65 | PTGS2 (0.45) | DRD2DRD3DRD4DRD1DRD5 | |
| SCHEMBL367003 | 0.65 | DRD2 (0.42) | DRD2DRD3DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926712-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[D]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007028131-A1 | 6-SUBSTITUTED 2,3,4,5-TETRAHYDRO-1H-BENZO[d]AZEPINES AS 5-HT2C RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2007-03-08 | — | — | WO | disclosed |