Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465084 | 1.00 | TOP1 (0.42) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL9172132 | 0.96 | TOP1 (0.39) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL12254047 | 0.79 | TYMP (0.33) | LMNA | |
| SCHEMBL17284856 | 0.79 | TOP1 (0.41) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL9147045 | 0.79 | TOP1 (0.37) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL11126839 | 0.77 | LMNA (0.46) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL8342267 | 0.77 | LMNA (0.46) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL9549571 | 0.77 | ZDHHC20 (0.37) | TOP1LMNAL3MBTL1PDE4ATDP1 | |
| SCHEMBL4812030 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL29288837 | 0.76 | LMNA (0.41) | TOP1LMNAL3MBTL1PDE4ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908788-A1 | Novel biomimetic hydrogel materials | The Regents of the University of California (US) | 2008-04-09 | — | — | EP | claimed |
| US-6552103-B1 | Soft contact lenses and biomedical implants | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | claimed |
| EP-1017737-A4 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2002-06-26 | — | — | EP | claimed |
| EP-1017737-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | The Regents of the University of California (US) | 2000-07-12 | — | — | EP | claimed |
| WO-1999011692-A1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-11 | — | — | WO | claimed |
| EP-0367886-B1 | Hydrophilic monomers, polymers thereof and their applications | GUEST ELCHROM SCIENT AG (CH) | 1995-04-19 | — | — | EP | claimed |
| US-5185466-A | Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis | KOZULIC BRANKO (CH) | 1993-02-09 | — | — | US | claimed |
| US-5104729-A | PROCESS FOR SURFACE MODIFYING A SUPPORT MEMBRANE AND PRODUCT PRODUCED | MONSANTO COMPANY (US) | 1992-04-14 | — | — | US | claimed |
| EP-0474617-A1 | Process for surface modifying a support membrane | MONSANTO COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| EP-0367886-A1 | Hydrophilic monomers, polymers thereof and their applications | Guest Elchrom Scientific AG (CH) | 1990-05-16 | — | — | EP | claimed |
| EP-1908788-A1 | Novel biomimetic hydrogel materials | The Regents of the University of California (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-1017737-B1 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2008-01-23 | — | — | EP | disclosed |
| US-6552103-B1 | Soft contact lenses and biomedical implants | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-04-22 | — | — | US | disclosed |
| EP-1017737-A4 | NOVEL BIOMIMETIC HYDROGEL MATERIALS | UNIV CALIFORNIA (US) | 2002-06-26 | — | — | EP | disclosed |
| US-6107365-A | A COPOLYMER OF METHACRYLATE FUNCTIONAL SULFOXIDE, SULFIDE OR SULFONE MONOMERS AND A COMONOMER SELECTED FROM HYDROPHILIC OR HYDROPHOBIC MATERIAL SELECTED FROM ACRYLMIDE, ACRYLATE, METHACRYLATE, SILOXANE, VINYL AND A DERIVATIVE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0367886-B1 | Hydrophilic monomers, polymers thereof and their applications | GUEST ELCHROM SCIENT AG (CH) | 1995-04-19 | — | — | EP | disclosed |
| US-5278270-A | Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis | ELCHROM LTD. (CH) | 1994-01-11 | — | — | US | disclosed |
| US-5202007-A | Separations using homo- or copolymers made from unsaturated hydroxyalkyl amides | ELCHROM SCIENTIFIC, AG (CH) | 1993-04-13 | — | — | US | disclosed |
| US-5185466-A | Hydrophilic and amphiphatic monomers, their polymers and gels and hydrophobic electrophoresis | KOZULIC BRANKO (CH) | 1993-02-09 | — | — | US | disclosed |
| EP-0367886-A1 | Hydrophilic monomers, polymers thereof and their applications | Guest Elchrom Scientific AG (CH) | 1990-05-16 | — | — | EP | disclosed |