Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4773901 | 0.85 | KCNQ2 (0.41) | KCNQ2NPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL4779864 | 0.82 | NOX1 (0.41) | MEN1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL4879715 | 0.76 | PIM1 (0.44) | HTTMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10095669 | 0.74 | HSD17B10 (0.51) | KCNQ2MTNR1BNPC1HTTMAPK1 | |
| SCHEMBL4780752 | 0.73 | NPC1 (0.44) | NPC1MAPTKDM4EHPGDRAB9A | |
| SCHEMBL8590356 | 0.69 | TUBB4A (0.48) | HTTMEN1ALDH1A1KMT2AMAPT | |
| SCHEMBL7556396 | 0.68 | NPC1 (0.69) | KCNQ2MTNR1BNPC1HTTMAPK1 | |
| SCHEMBL10095942 | 0.67 | GRIK2 (0.54) | KCNQ2MTNR1BNPC1HTTMAPK1 | |
| SCHEMBL982904 | 0.67 | MTNR1B (0.46) | KCNQ2MTNR1BNPC1HTTMAPK1 | |
| SCHEMBL10096283 | 0.66 | MTNR1B (0.44) | KCNQ2MTNR1BNPC1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |