Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.44 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779864 | 0.88 | NOX1 (0.41) | PIM1FNTAFNTBDYRK1ACLK1 | |
| SCHEMBL4774067 | 0.80 | RXRA (0.44) | HPGDMEN1KMT2AGRIA2GRIA4 | |
| SCHEMBL10097343 | 0.78 | PIM1 (0.50) | PIM1DYRK1ACLK1CLK2CLK4 | |
| SCHEMBL4778723 | 0.70 | ALDH1A1 (0.33) | HPGDMEN1HTTKMT2ANPSR1 | |
| SCHEMBL10097341 | 0.68 | MAPK13 (0.48) | DYRK1ACLK1CLK2CLK4DYRK1B | |
| SCHEMBL8589109 | 0.68 | NOX1 (0.46) | HPGDMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29731230 | 0.66 | ACMSD (0.67) | PIM1PIM2KDM4EGAACYP11B1 | |
| SCHEMBL28843348 | 0.66 | ACMSD (0.67) | PIM1PIM2KDM4EGAACYP11B1 | |
| SCHEMBL8590356 | 0.66 | TUBB4A (0.48) | HPGDMEN1HTTKMT2AKDM4E | |
| SCHEMBL10095669 | 0.65 | HSD17B10 (0.51) | HPGDMEN1HTTKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979315-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007084435-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |