Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774637 | 0.85 | KCNQ2 (0.48) | KCNQ2BRAFHPGDALDH1A1KDM4E | |
| SCHEMBL4774067 | 0.69 | RXRA (0.44) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL10095669 | 0.69 | HSD17B10 (0.51) | KCNQ2HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL9515073 | 0.68 | LMNA (0.69) | HPGDALDH1A1KDM4ENPC1CRHBP | |
| SCHEMBL981395 | 0.67 | PFKFB2 (0.42) | KCNQ2BRAFHPGDALDH1A1KDM4E | |
| SCHEMBL10096350 | 0.66 | ALDH1A1 (0.44) | KCNQ2BRAFHPGDALDH1A1NPC1 | |
| SCHEMBL12105784 | 0.65 | PFKFB2 (0.50) | KCNQ2HPGDALDH1A1KDM4ENPSR1 | |
| SCHEMBL2033732 | 0.63 | RAB9A (0.56) | HPGDALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL11767621 | 0.62 | KDM4E (0.70) | HPGDALDH1A1KDM4ENPSR1HSD17B10 | |
| SCHEMBL11104056 | 0.61 | LMNA (0.69) | HPGDALDH1A1NPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984332-A2 | METHODS FOR TREATING HEPATITIS C | PTC Therapeutics, Inc. (US) | 2008-10-29 | — | — | EP | disclosed |
| WO-2007084413-A2 | METHODS FOR TREATING HEPATITIS C | PTC THERAPEUTICS, INC. (US) | 2007-07-26 | — | — | WO | disclosed |