Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026767 | 0.87 | ALDH1A1 (0.43) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL28351674 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL303434 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL9610823 | 0.84 | DRD2 (0.37) | PLA2G10PLA2G5CACNA1H | |
| SCHEMBL4180063 | 0.83 | CTSK (0.43) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL3470166 | 0.83 | PLA2G10 (0.41) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL27147241 | 0.83 | PLA2G10 (0.41) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL3799622 | 0.83 | PLA2G10 (0.41) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL14312161 | 0.81 | SIGMAR1 (0.48) | MEN1KMT2ANPC1RAB9APLA2G10 | |
| SCHEMBL13014173 | 0.80 | PLA2G10 (0.39) | ALOX15KMT2APLA2G10PLA2G5CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641770-A4 | SYNTHESIS OF TRIS N-ALKYLATED 1,4,7,10-TETRAAZACYCLODODECANES | UNIV HONG KONG (CN) | 2008-12-31 | — | — | EP | disclosed |
| EP-1641770-A1 | SYNTHESIS OF TRIS N-ALKYLATED 1,4,7,10-TETRAAZACYCLODODECANES | The University of Hong Kong (CN) | 2006-04-05 | — | — | EP | disclosed |
| US-20050033106-A1 | Synthesis of tris N-alkylated 1,4,7,10-tetraazacyclododecanes | UNIVERSITY OF HONG KONG (CN) | 2005-02-10 | — | — | US | disclosed |
| WO-2005003105-A1 | SYNTHESIS OF TRIS N-ALKYLATED 1,4,7,10-TETRAAZACYCLODODECANES | THE UNIVERSITY OF HONG KONG (CN) | 2005-01-13 | — | — | WO | disclosed |