Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774428 | 0.82 | KMT2A (0.46) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4020618 | 0.81 | KIF11 (0.41) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4021208 | 0.80 | GRIN2B (0.38) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4021213 | 0.80 | GRIN2B (0.38) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4022415 | 0.80 | GRIN2B (0.38) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4020371 | 0.80 | KIF11 (0.45) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4028765 | 0.80 | OPRD1 (0.38) | KIF11 | |
| SCHEMBL4022426 | 0.79 | BLM (0.43) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4019197 | 0.79 | KIF11 (0.39) | KIF11ALDH1A1USP2LMNAMAPT | |
| SCHEMBL4780207 | 0.79 | L3MBTL1 (0.37) | KIF11ALDH1A1USP2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |