Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777398 | 0.90 | KMT2A (0.45) | KDM4ELMNAALDH1A1GAATPSAB1 | |
| SCHEMBL4770946 | 0.84 | RECQL (0.39) | KDM4ELMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL4774938 | 0.83 | RECQL (0.49) | KDM4EPKMLMNASMN1; SMN2HTT | |
| SCHEMBL4793581 | 0.77 | RECQL (0.41) | LMNASMN1; SMN2ALDH1A1NAMPTCXCR3 | |
| SCHEMBL5571930 | 0.76 | ALDH1A1 (0.56) | KDM4EPKMLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4767621 | 0.74 | RECQL (0.49) | KDM4ELMNAALDH1A1GAATPSAB1 | |
| SCHEMBL5567967 | 0.73 | KDM4E (0.58) | KDM4EPKMLMNAALDH1A1GAA | |
| SCHEMBL5571928 | 0.69 | NAMPT (0.45) | KDM4EPKMLMNASMN1; SMN2HTT | |
| SCHEMBL4775217 | 0.68 | RECQL (0.56) | LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5571881 | 0.68 | ALDH1A1 (0.51) | LMNAALDH1A1GAADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942888-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056078-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |