Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD5 | P21918 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219832 | 0.88 | WNT3 (0.44) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4775951 | 0.86 | TDP1 (0.41) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL4776118 | 0.82 | KDM2B (0.51) | KDM2B | |
| SCHEMBL3515523 | 0.80 | LMNA (0.53) | — | |
| SCHEMBL3515528 | 0.80 | LMNA (0.53) | — | |
| SCHEMBL5339926 | 0.78 | TDP1 (0.48) | KDM4E | |
| SCHEMBL4780546 | 0.78 | CNR2 (0.41) | PARP14PARP10KDM2BKDM4E | |
| SCHEMBL4776003 | 0.77 | MGLL (0.48) | — | |
| SCHEMBL3088285 | 0.76 | MCL1 (0.46) | — | |
| SCHEMBL5172182 | 0.76 | MCL1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |