Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172182 | 0.85 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL3088285 | 0.85 | MCL1 (0.46) | ALDH1A1 | |
| SCHEMBL3518713 | 0.85 | HPGD (0.51) | ALDH1A1 | |
| SCHEMBL3518717 | 0.85 | HPGD (0.51) | ALDH1A1 | |
| SCHEMBL5339926 | 0.85 | TDP1 (0.48) | — | |
| SCHEMBL3515035 | 0.85 | MGLL (0.43) | MGLL | |
| SCHEMBL3515032 | 0.85 | MGLL (0.43) | MGLL | |
| SCHEMBL4779559 | 0.82 | HPGD (0.44) | MGLLCA2ALDH1A1MAPT | |
| SCHEMBL4776118 | 0.82 | KDM2B (0.51) | MGLLALDH1A1 | |
| SCHEMBL3515528 | 0.82 | LMNA (0.53) | MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |