SCHEMBL477608

SCHEMBL477608

CCCCCCCCCCC(O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
ASAH1 Q13510 2/20 0.57
RIPK1 Q13546 1/20 0.55
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 2/20 0.54
CSNK1E P49674 1/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
NAAA Q02083 2/20 0.51
CERT1 Q9Y5P4 3/20 0.50
ACER2 Q5QJU3 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
OPRM1 P35372 1/20 0.47
OPRD1 P41143 1/20 0.47
OPRK1 P41145 1/20 0.47
OPRL1 P41146 1/20 0.47
HTR2A P28223 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30975296 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL7120698 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL477567 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL477546 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL477511 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL8193119 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL405975 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL477578 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL22491606 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E
SCHEMBL29199312 1.00 LMNA (0.59) LMNAASAH1RIPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0805825-B1 GELS FROM ANHYDRIDE-CONTAINING POLYMERS TYCO ELECTRONICS CORP (US) 2000-08-23 EP claimed
US-5849824-A Gels from anhydride-containing polymers RAYCHEM CORPORATION (US) 1998-12-15 US claimed
EP-0805825-A1 GELS FROM ANHYDRIDE-CONTAINING POLYMERS RAYCHEM CORPORATION (US) 1997-11-12 EP claimed
WO-1996023007-A1 GELS FROM ANHYDRIDE-CONTAINING POLYMERS RAYCHEM CORPORATION (US) 1996-08-01 WO claimed
US-8563786-B2 Method for producing optically active alcohol MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-12 US disclosed
EP-2412694-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds GILEAD SCIENCES, INC. 2008-03-27 US disclosed
EP-1742642-A2 PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2007-01-17 EP disclosed
US-7112608-B2 Hydroxyphenylundecane, a process for their production and their use SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-09-26 US disclosed
US-7112608-B2 Hydroxyphenylundecane, a process for their production and their use SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-09-26 US disclosed
US-7112608-B2 Hydroxyphenylundecane, a process for their production and their use SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2006-09-26 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
CN-1055375-A The copolymer compositions that contains multipolymer and one or more slip additives SHELL INT RESEARCH (NL) 1991-10-16 CN disclosed
EP-0450695-A1 Copolymer compositions comprising a copolymer and one or more lubricating additives SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-10-09 EP disclosed
US-4894480-A Phenyl substituted-2,4,6,8-nonatetraenoic acid HOFFMANN-LA ROCHE INC. (US) 1990-01-16 US disclosed
US-4883614-A TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS HOFFMAN-LA ROCHE INC. (US) 1989-11-28 US disclosed
US-4883613-A TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1989-11-28 US disclosed
US-4780251-A ANTIRHEUMATIC AGENTS, IMMUNOSUPPRESSANTS HOFFMAN-LA ROCHE INC. (US) 1988-10-25 US disclosed
US-4648996-A ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS HOFFMANN-LA ROCHE INC. (US) 1987-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, FHIT LMNA 1422/4885ASAH1 3422/4885RIPK1 4112/4885
US-20080076738-A1 Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds TYMP, PNP, PIKFYVE LMNA 2126/4885ASAH1 1503/4885RIPK1 1215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.