Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778028 | 1.00 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1USP30 | |
| SCHEMBL8220552 | 0.91 | OPRD1 (0.46) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4778904 | 0.91 | OPRD1 (0.46) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4781736 | 0.88 | OPRD1 (0.43) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4781630 | 0.87 | OPRD1 (0.38) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4780899 | 0.85 | IRAK1 (0.39) | — | |
| SCHEMBL4795530 | 0.84 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4796605 | 0.83 | IDO1 (0.39) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4794937 | 0.83 | IDO1 (0.39) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4793792 | 0.82 | BRD4 (0.34) | OPRD1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |