Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 10/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781926 | 0.90 | PIK3CD (0.35) | PFKFB3 | |
| SCHEMBL4793792 | 0.90 | BRD4 (0.34) | PFKFB3CREBBP | |
| SCHEMBL4781704 | 0.88 | CREBBP (0.35) | CREBBP | |
| SCHEMBL4781736 | 0.85 | OPRD1 (0.43) | — | |
| SCHEMBL4778028 | 0.85 | OPRD1 (0.36) | — | |
| SCHEMBL4776163 | 0.85 | OPRD1 (0.36) | — | |
| SCHEMBL4778904 | 0.84 | OPRD1 (0.46) | — | |
| SCHEMBL8220552 | 0.84 | OPRD1 (0.46) | — | |
| SCHEMBL4794937 | 0.83 | IDO1 (0.39) | — | |
| SCHEMBL4796605 | 0.83 | IDO1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |