Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778904 | 1.00 | OPRD1 (0.46) | OPRD1BACE1ALDH1A1KMT2AKDM4E | |
| SCHEMBL4776163 | 0.91 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4778028 | 0.91 | OPRD1 (0.36) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4781848 | 0.90 | OPRD1 (0.53) | OPRD1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4794880 | 0.90 | OPRD1 (0.53) | OPRD1ALDH1A1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL4834221 | 0.88 | OPRD1 (0.42) | OPRD1ALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL4795530 | 0.87 | OPRD1 (0.36) | OPRD1ALDH1A1KDM4EKCNH2OPRM1 | |
| SCHEMBL4781736 | 0.87 | OPRD1 (0.43) | OPRD1OPRM1OPRK1OPRL1 | |
| SCHEMBL4780899 | 0.84 | IRAK1 (0.39) | — | |
| SCHEMBL4796605 | 0.82 | IDO1 (0.39) | OPRD1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |