Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780899 | 0.90 | IRAK1 (0.39) | CREBBPPFKFB3 | |
| SCHEMBL4781926 | 0.85 | PIK3CD (0.35) | PIK3CDPIP5K1CPIK3CAPI4KAPIK3CG | |
| SCHEMBL4781736 | 0.83 | OPRD1 (0.43) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4776163 | 0.82 | OPRD1 (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4778028 | 0.82 | OPRD1 (0.36) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8220552 | 0.82 | OPRD1 (0.46) | KMT2AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4778904 | 0.82 | OPRD1 (0.46) | KMT2AOPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4796605 | 0.79 | IDO1 (0.39) | OPRM1OPRD1OPRK1OPRL1GSK3B | |
| SCHEMBL4794937 | 0.79 | IDO1 (0.39) | OPRM1OPRD1OPRK1OPRL1GSK3B | |
| SCHEMBL4781704 | 0.77 | CREBBP (0.35) | BRD4CREBBPOPRD1GSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |