Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4776865 | 0.84 | MET (0.73) | MET | |
| SCHEMBL4815879 | 0.83 | MET (0.66) | MET | |
| SCHEMBL4765185 | 0.81 | MET (0.74) | MET | |
| SCHEMBL8286877 | 0.81 | MET (0.66) | MET | |
| SCHEMBL4819497 | 0.81 | MET (0.76) | MET | |
| SCHEMBL4252606 | 0.80 | MET (0.70) | MET | |
| SCHEMBL4769597 | 0.80 | MET (0.70) | MET | |
| SCHEMBL4819150 | 0.80 | MET (0.69) | MET | |
| SCHEMBL4769514 | 0.80 | MET (0.68) | MET | |
| SCHEMBL4767120 | 0.80 | MET (0.74) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709043-B1 | PYRROLOPYRIDINE-SUBSTITUTED BENZOL DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2008-12-03 | — | — | EP | disclosed |
| EP-1709043-B1 | PYRROLOPYRIDINE-SUBSTITUTED BENZOL DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2008-12-03 | — | — | EP | disclosed |
| US-20080249105-A1 | Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases | BAYER HEALTHCARE AG (DE) | 2008-10-09 | — | — | US | disclosed |
| US-20080249105-A1 | Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases | BAYER HEALTHCARE AG (DE) | 2008-10-09 | — | — | US | disclosed |
| EP-1709043-A1 | PYRROLOPYRIDINE-SUBSTITUTED BENZOL DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | Bayer HealthCare AG (DE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005058891-A1 | PYRROLOPYRIDINE-SUBSTITUTED BENZOL DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058891-A1 | PYRROLOPYRIDINE-SUBSTITUTED BENZOL DERIVATIVES FOR TREATING CARDIOVASCULAR DISEASES | BAYER HEALTHCARE AG (DE) | 2005-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249105-A1 | Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases | PHB2, PHB1, TNNT2 | MET 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.