Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 3/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7429490 | 0.96 | MAP2K4 (0.39) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL7420704 | 0.86 | KDM4E (0.39) | TTKPDPK1KDM4EHIF1AYTHDC1 | |
| SCHEMBL2723270 | 0.80 | MAP2K4 (0.49) | MAP2K4TTKKDM4EHIF1AYTHDC1 | |
| SCHEMBL8877409 | 0.78 | MAP2K4 (0.44) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL1648452 | 0.78 | MAP2K4 (0.44) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL16252836 | 0.76 | MAP2K4 (0.43) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL16475286 | 0.76 | PDPK1 (0.56) | PDPK1KDM4EKDRFLT3CDK1 | |
| SCHEMBL25696142 | 0.75 | MAP2K4 (0.35) | MAP2K4TTKKDM4EHIF1AYTHDC1 | |
| SCHEMBL18368384 | 0.74 | CYP1A2 (0.41) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL27010919 | 0.74 | CYP1A2 (0.41) | MAP2K4TTKPDPK1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902044-A1 | 5-HTX MODULATORS | Bio Medisinsk Innovasjon AS (NO) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007007072-A1 | 5-HTX MODULATORS | BIO-MEDISINSK INNOVASJON AS (NO) | 2007-01-18 | — | — | WO | disclosed |