Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777030 | 0.86 | MAP2K4 (0.41) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| Oxalic Acid SCHEMBL7429490 | 0.85 | MAP2K4 (0.39) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL570533 | 0.79 | HAO1 (0.50) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| Hydrochloric Acid SCHEMBL9444673 | 0.78 | HAO1 (0.49) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL28497966 | 0.77 | PARP1 (0.45) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL1967918 | 0.77 | GPR17 (0.43) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL28503102 | 0.76 | PARP1 (0.44) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL16240884 | 0.76 | CTNNB1 (0.44) | KDM4EHIF1AYTHDC1STAT3CDK2 | |
| SCHEMBL7374273 | 0.76 | GAA (0.54) | TTKCDK5DYRK1ACLK4PRKAG1 | |
| SCHEMBL7409257 | 0.75 | KDM4E (0.39) | KDM4EHIF1AYTHDC1STAT3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999017772-A1 | 5HT4 AGONISTS AND ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |