Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1648452 | 0.83 | MAP2K4 (0.44) | MAP2K4GAATTKPDPK1KDM4E | |
| SCHEMBL16252836 | 0.81 | MAP2K4 (0.43) | MAP2K4GAATTKPDPK1KDM4E | |
| SCHEMBL2723270 | 0.81 | MAP2K4 (0.49) | MAP2K4TTKKDM4EHIF1AYTHDC1 | |
| SCHEMBL4777030 | 0.78 | MAP2K4 (0.41) | MAP2K4GAATTKPDPK1KDM4E | |
| SCHEMBL2021782 | 0.78 | KDR (0.52) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL2721094 | 0.76 | NOS1 (0.44) | MAP2K4NPSR1TTKTHRBRAB9A | |
| Oxalic Acid SCHEMBL7429490 | 0.74 | MAP2K4 (0.39) | MAP2K4TTKPDPK1KDM4EHIF1A | |
| SCHEMBL10368038 | 0.74 | PDPK1 (0.61) | MAP2K4GAAPDPK1KDM4EIMPDH2 | |
| SCHEMBL3802281 | 0.74 | IMPDH2 (0.44) | MAP2K4GAANPSR1TTKTHRB | |
| SCHEMBL82761 | 0.73 | KDM4E (0.62) | GAARAB9APDPK1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684003-A | GASTROINTESTINAL DISORDERS OR ANTIULCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |