Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726369 | 0.80 | CA12 (0.41) | CA12CA1CA2CA9POLB | |
| SCHEMBL27793451 | 0.78 | TDP1 (0.56) | POLBLMNARAB9AALDH1A1 | |
| SCHEMBL2321117 | 0.76 | LMNA (0.56) | CA12CA1CA2CA9POLB | |
| SCHEMBL234454 | 0.75 | LMNA (0.62) | CA12CA1CA2CA9POLB | |
| SCHEMBL7975327 | 0.75 | LMNA (0.44) | CA12CA1CA2CA9POLB | |
| SCHEMBL8058893 | 0.74 | ALDH1A1 (0.46) | POLBLMNASMN1; SMN2ATMCTRB1 | |
| SCHEMBL8446295 | 0.74 | SMN1; SMN2 (0.46) | POLBLMNASMN1; SMN2ATMCTRB1 | |
| SCHEMBL30386641 | 0.74 | ITGB3 (0.43) | CA12CA1CA2CA9POLB | |
| SCHEMBL29202480 | 0.74 | ITGB3 (0.43) | CA12CA1CA2CA9POLB | |
| SCHEMBL29777624 | 0.74 | POLB (0.56) | CA12CA1CA2CA9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008003079-A1 | COMPOSITIONS AND METHODS PERTAINING TO GUANYLATION OF PNA OLIGOMERS | APPLERA CORPORATION (US) | 2008-01-03 | — | — | WO | disclosed |