Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 12/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778639 | 0.84 | SLC2A1 (0.48) | TOP2A | |
| SCHEMBL27985054 | 0.79 | KDM4E (0.44) | CACNA2D1 | |
| SCHEMBL25532696 | 0.75 | SIGMAR1 (0.59) | CACNA2D1 | |
| SCHEMBL9796522 | 0.75 | SIGMAR1 (0.59) | CACNA2D1 | |
| Hydrochloric Acid SCHEMBL3299437 | 0.72 | RAB9A (0.50) | — | |
| SCHEMBL13739508 | 0.71 | CACNA2D1 (0.41) | CACNA2D1 | |
| SCHEMBL3887726 | 0.71 | CACNA2D1 (0.41) | CACNA2D1 | |
| SCHEMBL4777085 | 0.70 | CACNA2D1 (0.40) | CACNA2D1 | |
| SCHEMBL28241436 | 0.70 | KDM4E (0.55) | CACNA2D1 | |
| SCHEMBL6266749 | 0.69 | KDM4E (0.53) | CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010984-A9 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | UNIV PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008010984-A2 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-01-24 | — | — | WO | claimed |
| WO-2008010984-A9 | ACRIDINE ACTIVATION OF P53 AND USES THEREOF | UNIV PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | disclosed |