Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777093 | 0.79 | CACNA2D1 (0.52) | CACNA2D1 | |
| SCHEMBL4778639 | 0.78 | SLC2A1 (0.48) | KDM4EALDH1A1GLAHPGDCASP1 | |
| Hydrochloric Acid SCHEMBL3299437 | 0.78 | RAB9A (0.50) | KDM4EALDH1A1GLAHPGDCASP1 | |
| SCHEMBL2484563 | 0.70 | SCN4A (0.47) | — | |
| SCHEMBL28241436 | 0.68 | KDM4E (0.55) | KDM4EALDH1A1GLAHPGDCASP1 | |
| SCHEMBL8190259 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1GLAHPGDCASP1 | |
| SCHEMBL6266749 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1GLAHPGDCASP1 | |
| SCHEMBL31139216 | 0.66 | ACHE (0.56) | KDM4EALDH1A1HSD17B10CHRM2ADRA2A | |
| SCHEMBL31139207 | 0.66 | ACHE (0.56) | KDM4EALDH1A1HSD17B10CHRM2ADRA2A | |
| SCHEMBL17423904 | 0.66 | KDM4E (0.50) | KDM4EALDH1A1GLAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230805-A | Bridge-linked acridine dimer and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2014-12-24 | — | — | CN | claimed |
| CN-104230805-A | Bridge-linked acridine dimer and preparation method and application thereof | UNIV GUANGXI CHINESE MEDICINE | 2014-12-24 | — | — | CN | disclosed |