Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230674 | 0.72 | LTA4H (0.58) | LTA4HSIGMAR1HTTCA4ALDH1A1 | |
| SCHEMBL570480 | 0.72 | LTA4H (1.00) | LTA4HSIGMAR1HTTCA4NPC1 | |
| SCHEMBL2355634 | 0.72 | LTA4H (0.75) | LTA4HSIGMAR1HTTCA4NPC1 | |
| SCHEMBL4623866 | 0.71 | LTA4H (0.67) | LTA4HSIGMAR1HTTCA4TRPA1 | |
| SCHEMBL5035885 | 0.70 | LTA4H (0.46) | LTA4HSIGMAR1CA4TRPA1NPC1 | |
| SCHEMBL6429953 | 0.69 | LTA4H (0.69) | LTA4HSIGMAR1HTTCA4NPC1 | |
| Benzyl Bromide SCHEMBL10545816 | 0.69 | LTA4H (0.69) | LTA4HSIGMAR1HTTCA4TRPA1 | |
| SCHEMBL3036840 | 0.69 | LTA4H (0.69) | LTA4HSIGMAR1HTTCA4NPC1 | |
| SCHEMBL5632470 | 0.69 | LTA4H (0.69) | LTA4HSIGMAR1NPC1TDP1L3MBTL1 | |
| Benzylamine SCHEMBL7484124 | 0.69 | LTA4H (0.69) | LTA4HSIGMAR1HTTCA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675851-B1 | METHOD FOR PRODUCING N-SUBSTITUTED 3BETA-AMINONORTROPANES | BOEHRINGER INGELHEIM INT (DE) | 2008-08-20 | — | — | EP | disclosed |
| EP-1675851-A1 | METHOD FOR PRODUCING N-SUBSTITUTED 3BETA-AMINONORTROPANES | Boehringer Ingelheim International GmbH (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037831-A1 | METHOD FOR PRODUCING N-SUBSTITUTED 3β-AMINONORTROPANES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-04-28 | — | — | WO | disclosed |