Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | IDH2 | P48735 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160376 | 0.84 | PTGS2 (0.54) | RORCHSD17B10S1PR1PTGS2 | |
| SCHEMBL1068740 | 0.84 | CA12 (0.50) | RORCTDP1PTGS2 | |
| SCHEMBL28820911 | 0.84 | RORC (0.49) | RORCS1PR1S1PR3MMP2MMP3 | |
| Hydrochloric Acid SCHEMBL16015050 | 0.83 | CA12 (0.49) | RORCTDP1PTGS2 | |
| SCHEMBL28971603 | 0.83 | PDE3B (0.43) | ALDH1A1HSD17B10TDP1PTGS2IDH2 | |
| SCHEMBL4618175 | 0.81 | CA1 (0.50) | ALDH1A1S1PR1S1PR3 | |
| SCHEMBL28022855 | 0.80 | RORC (0.46) | RORCALDH1A1PTGS2IDH2NR3C1 | |
| SCHEMBL30270478 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TDP1MMP2PTGS2 | |
| SCHEMBL18424825 | 0.79 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TDP1PTGS2 | |
| SCHEMBL4617666 | 0.79 | PTGS2 (0.54) | S1PR1S1PR3MMP2MMP3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024784-A1 | ALKYLSULFONAMIDE-SUBSTITUTED TRIAZOLES AS MATRIX METALLOPROTEASE INHIBITORS | ARRAY BIOPHARMA, INC. (US) | 2008-02-28 | — | — | WO | disclosed |