Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022364 | 0.88 | NPC1 (0.45) | RORCNPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL28160376 | 0.83 | PTGS2 (0.54) | RORCRAB9ALMNANR1H3KIF11 | |
| SCHEMBL1068740 | 0.80 | CA12 (0.50) | RORCLMNAKIF11PTGS2 | |
| SCHEMBL28820911 | 0.80 | RORC (0.49) | RORCHDAC6TSHRIDH2 | |
| SCHEMBL4777733 | 0.80 | RORC (0.46) | RORCNR3C1ALDH1A1IDH2PTGS2 | |
| Hydrochloric Acid SCHEMBL16015050 | 0.79 | CA12 (0.49) | RORCLMNAKIF11PTGS2 | |
| SCHEMBL19145383 | 0.76 | L3MBTL1 (0.44) | ALDH1A1RAB9ALMNAHDAC4HDAC6 | |
| SCHEMBL8490622 | 0.76 | LMNA (0.48) | NPC1LMNA | |
| SCHEMBL16599260 | 0.75 | ALDH1A1 (0.49) | NPC1ALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL20765376 | 0.75 | MAPT (0.55) | ALDH1A1LMNAHDAC4HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |