Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777821 | 1.00 | RECQL (0.53) | RECQLTDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6686701 | 0.77 | TSPO (0.51) | TDP1ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL29176318 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29750390 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL29690244 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6769397 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6769396 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL30152192 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL3742734 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL12315710 | 0.76 | RECQL (0.59) | RECQLTDP1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024151-A2 | SALTS AND CO-CRYSTALS OF PYRAZOLOPYRIMIDINE COMPOUNDS, COMPOSITIONS THEREOF AND METHODS FOR THEIR PRODUCTION AND USE | DOV PHARMACEUTICAL, INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| US-20080045547-A1 | Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use | DOV PHARMACEUTICAL, INC. | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045547-A1 | Salts And Co-Crystals of Pyrazolopyrimidine Compounds, Compositions Thereof And Methods For Their Production And Use | PNPO, INPP5A, P2RY6 | RECQL 924/4885TDP1 1027/4885ALDH1A1 2967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.