Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135577 | 0.81 | LMNA (0.46) | KMT2AMEN1MAPTRXFP1LMNA | |
| SCHEMBL1135816 | 0.78 | MAPT (0.51) | KMT2AMEN1MAPTRXFP1LMNA | |
| SCHEMBL2890226 | 0.72 | F2 (0.39) | MEN1LMNACA12CA1CA2 | |
| SCHEMBL7478269 | 0.70 | MMP3 (0.57) | KMT2AMEN1LMNAHDAC4HDAC6 | |
| SCHEMBL4876765 | 0.67 | KMT2A (0.52) | KMT2AMEN1LMNAHDAC4HDAC6 | |
| SCHEMBL28057794 | 0.66 | MEN1 (0.47) | KMT2AMEN1MAPTRXFP1LMNA | |
| SCHEMBL12261100 | 0.66 | KMT2A (0.52) | KMT2AMEN1MAPTRXFP1LMNA | |
| SCHEMBL407669 | 0.65 | ALDH1A1 (0.73) | KMT2AMEN1MAPTRXFP1LMNA | |
| SCHEMBL14736416 | 0.65 | ALDH1A1 (0.53) | KMT2AMEN1MAPTLMNAALDH1A1 | |
| SCHEMBL5450808 | 0.65 | ALDH1A1 (0.62) | KMT2AMEN1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006078621-A9 | 2-PHENOXY-N- (1, 3 , 4-THIADIZOL-2-YL) PYRIDIN-3-AMINE DERIVATIVES AND RELATED COMPOUNDS AS P2Y1 RECEPTOR INHIBITORS FOR THE TREATMENT OF THROMBOEMBOLIC DISORDERS | BRISTOL MYERS SQUIBB CO (US) | 2008-06-19 | — | — | WO | disclosed |