Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | LITAF | Q99732 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262116 | 0.87 | TOP2A (0.39) | TOP2ATOP2BTNFLITAF | |
| SCHEMBL28398003 | 0.81 | MGAM (0.41) | GSK3B | |
| SCHEMBL4305779 | 0.80 | TOP2A (0.42) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL30572775 | 0.79 | KDM4E (0.57) | KCNH2 | |
| SCHEMBL9428229 | 0.77 | TOP2A (0.40) | TOP2ATOP2BKCNH2GSK3B | |
| SCHEMBL30564284 | 0.76 | KDM4E (0.49) | KCNH2 | |
| SCHEMBL3337171 | 0.75 | KCNH2 (0.41) | KCNH2GSK3B | |
| SCHEMBL4515223 | 0.75 | ALDH1A1 (0.38) | TOP2ATOP2BKCNH2 | |
| SCHEMBL4518378 | 0.74 | TNF (0.35) | TOP2ATOP2BTNFLITAF | |
| SCHEMBL28404470 | 0.74 | ADRB2 (0.39) | TOP2ATOP2BTNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992626-A1 | Process for the preparation of moxifloxacin hydrochloride | Sandoz AG (CH) | 2008-11-19 | — | — | EP | disclosed |