Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | LITAF | Q99732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778334 | 0.87 | TOP2A (0.41) | TOP2ATOP2BTNFLITAF | |
| SCHEMBL3129267 | 0.80 | TOP2A (0.39) | TOP2ATOP2B | |
| SCHEMBL28398003 | 0.70 | MGAM (0.41) | — | |
| SCHEMBL30572775 | 0.70 | KDM4E (0.57) | — | |
| SCHEMBL7810922 | 0.68 | ADRB2 (0.58) | TOP2ATOP2B | |
| SCHEMBL4305779 | 0.68 | TOP2A (0.42) | TOP2ATOP2B | |
| SCHEMBL30564284 | 0.67 | KDM4E (0.49) | — | |
| SCHEMBL9428229 | 0.65 | TOP2A (0.40) | TOP2ATOP2B | |
| SCHEMBL23037281 | 0.65 | TOP2A (0.47) | TOP2ATOP2B | |
| Fluoride SCHEMBL7804252 | 0.64 | TOP2A (0.56) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436367-A | 3, 4-difluorobenzoic acid derivatives | SANKO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |