Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778394 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL2404507 | 0.75 | CA1 (0.38) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL13691537 | 0.73 | CA1 (0.52) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL31630110 | 0.73 | MMP2 (0.49) | ALDH1A1MEN1KMT2ATSHRCA1 | |
| SCHEMBL14039395 | 0.73 | MMP2 (0.52) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL31630104 | 0.73 | MMP2 (0.52) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL31630207 | 0.73 | MMP2 (0.49) | ALDH1A1MEN1KMT2ATSHRCA1 | |
| SCHEMBL31630053 | 0.73 | MMP2 (0.52) | ALDH1A1MEN1KMT2ATSHRCYP2C9 | |
| SCHEMBL10443020 | 0.72 | SLC1A2 (0.50) | MEN1KMT2ASLC1A2 | |
| SCHEMBL26694878 | 0.71 | STAT3 (0.39) | ALDH1A1MEN1KMT2ATSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939625-A2 | Methods for ligand discovery | Sunesis Pharmaceuticals, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |