Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780075 | 0.79 | PTGER4 (0.50) | PTGER4LMNAALDH1A1KDM4EUSP2 | |
| SCHEMBL4779161 | 0.77 | PTGER4 (0.48) | CYP11B1PTGER4LMNAKDM4EHDAC6 | |
| SCHEMBL8156486 | 0.74 | PTGER4 (0.55) | PTGER4LMNAALDH1A1KDM4EUSP2 | |
| SCHEMBL689666 | 0.74 | CYP19A1 (0.64) | PTGER4LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2717858 | 0.73 | CYP11B1 (0.46) | CYP11B1CYP11B2HDAC6 | |
| SCHEMBL4775757 | 0.73 | PTGER4 (0.46) | PTGER4LMNAHDAC6PSMD14CNR2 | |
| SCHEMBL17060211 | 0.72 | CYP19A1 (0.58) | ALDH1A1KDM4ETSHRHSD17B10HDAC6 | |
| SCHEMBL4780793 | 0.72 | PTGER4 (0.55) | PTGER4LMNAKDM4EMAPTHDAC6 | |
| SCHEMBL28392221 | 0.72 | P2RX4 (0.61) | PTGER4LMNAALDH1A1KDM4ETSHR | |
| SCHEMBL5325246 | 0.72 | PTGER4 (0.44) | CYP11B1CYP11B2PTGER4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |