Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642543 | 0.97 | TSHR (0.40) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL7080606 | 0.83 | HSD17B10 (0.36) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL17070916 | 0.77 | PSMD14 (0.31) | PSMD14 | |
| SCHEMBL19760869 | 0.77 | PSMD14 (0.30) | PSMD14 | |
| SCHEMBL22099887 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAPSMD14 | |
| SCHEMBL17536132 | 0.77 | HSD17B10 (0.38) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL17294176 | 0.73 | ALDH1A1 (0.43) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL2376039 | 0.73 | HSD17B10 (0.39) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL21292107 | 0.72 | ALDH1A1 (0.36) | TSHRHSD17B10ALDH1A1KDM4CLMNA | |
| SCHEMBL12481270 | 0.72 | TSHR (0.50) | TSHRHSD17B10ALDH1A1KDM4CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464061-B2 | N-hydroxylamino-barbituric acid derivatives | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-10-11 | — | — | US | disclosed |
| US-20160060229-A1 | N-HYDROXYLAMINO-BARBITURIC ACID DERIVATIVES | NATIONAL SCIENCE FOUNDATION | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060229-A1 | N-HYDROXYLAMINO-BARBITURIC ACID DERIVATIVES | TNNT2, TNNI3, TNNC1 | TSHR 2369/4885HSD17B10 607/4885ALDH1A1 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.