Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778521 | 0.92 | SLC40A1 (0.51) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL3091703 | 0.90 | CCR9 (0.43) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL4727559 | 0.88 | SLC40A1 (0.51) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL30304828 | 0.88 | SLC40A1 (0.51) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL3078414 | 0.87 | SLC40A1 (0.57) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL31478924 | 0.87 | SLC40A1 (0.57) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL4780299 | 0.86 | CYP3A4 (0.41) | MEN1KMT2ALMNAAXLBRAF | |
| SCHEMBL4777143 | 0.86 | SLC40A1 (0.49) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL4781896 | 0.85 | SLC40A1 (0.53) | SLC40A1MEN1KMT2ACLK1GAA | |
| SCHEMBL3097960 | 0.85 | AXL (0.53) | SLC40A1MEN1KMT2ACLK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | claimed |
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| WO-2005113490-A1 | SULFONE-CONTAINING PRODRUGS | ICAGEN, INC. (US) | 2005-12-01 | — | — | WO | disclosed |
| US-20050267032-A1 | Sulfone-containing prodrugs | ICAGEN, INC. (US) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267032-A1 | Sulfone-containing prodrugs | KCNQ5, KCNE1, KCNH2 | SLC40A1 719/4885MEN1 2143/4885KMT2A 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.