Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802258 | 0.86 | HPGD (0.62) | ALDH1A1MAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL4959294 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTTDP1SMN1; SMN2HPGD | |
| SCHEMBL17817419 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTTDP1SMN1; SMN2HPGD | |
| SCHEMBL4493393 | 0.77 | MAPK8 (0.68) | ALDH1A1MAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL5106577 | 0.77 | KMT2A (0.66) | ALDH1A1MAPTTDP1SMN1; SMN2HPGD | |
| SCHEMBL7311219 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTTDP1SMN1; SMN2HPGD | |
| SCHEMBL9667534 | 0.76 | KMT2A (0.74) | ALDH1A1MAPTTDP1CYP1A2HPGD | |
| SCHEMBL1367369 | 0.75 | NPC1 (0.71) | ALDH1A1MAPTSMN1; SMN2HPGDL3MBTL1 | |
| SCHEMBL13456099 | 0.74 | MAPK14 (0.57) | ALDH1A1SMN1; SMN2CYP1A2CYP2C19HPGD | |
| SCHEMBL2106155 | 0.74 | NPC1 (0.66) | ALDH1A1MAPTSMN1; SMN2HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987042-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | sanofi-aventis (FR) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093365-A2 | NOVEL AMINO ALCOHOL-SUBSTITUTED ARYLTHIENOPYRIMIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2007-08-23 | — | — | WO | disclosed |