Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 2/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959294 | 0.94 | ALDH1A1 (0.63) | ALDH1A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL24104683 | 0.90 | MAPK8 (0.62) | ALDH1A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL5106577 | 0.89 | KMT2A (0.66) | ALDH1A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL4787145 | 0.82 | KMT2A (0.64) | ALDH1A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL4958864 | 0.80 | ABCC1 (0.60) | ALDH1A1KMT2ATDP1MEN1MAPT | |
| SCHEMBL5294918 | 0.80 | MAPK8 (0.68) | ALDH1A1KMT2AMEN1MAPTCASP3 | |
| SCHEMBL4749588 | 0.79 | SMN1; SMN2 (0.67) | ALDH1A1KMT2AMEN1MAPTCASP3 | |
| SCHEMBL7933290 | 0.79 | MAPK8 (0.66) | ALDH1A1KMT2AMEN1MAPTCASP3 | |
| SCHEMBL28722481 | 0.79 | MAPK8 (0.66) | ALDH1A1KMT2AMEN1MAPTCASP3 | |
| SCHEMBL16760967 | 0.79 | MAPK8 (0.66) | ALDH1A1KMT2AMEN1MAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | ALDH1A1 999/4885KMT2A 411/4885TDP1 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.