Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 3/20 | 0.40 |
| ▸ | BRAF | P15056 | 12/20 | 0.37 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781339 | 0.93 | BRAF (0.43) | DDTBRAFRAF1 | |
| SCHEMBL4779575 | 0.90 | ACKR3 (0.34) | DDTBRAFKLKB1 | |
| SCHEMBL4782901 | 0.90 | BRAF (0.45) | DDTBRAFRAF1 | |
| SCHEMBL4783530 | 0.90 | ACKR3 (0.34) | DDTBRAFKLKB1 | |
| SCHEMBL4781343 | 0.83 | BRAF (0.53) | BRAFRAF1 | |
| SCHEMBL4779581 | 0.82 | MAPK14 (0.39) | DDTBRAFRAF1 | |
| SCHEMBL4778554 | 0.78 | DDT (0.42) | DDT | |
| SCHEMBL4730805 | 0.78 | DDT (0.42) | DDTBRAFRAF1 | |
| SCHEMBL4779207 | 0.77 | NR1I2 (0.38) | DDTKLKB1 | |
| SCHEMBL4780442 | 0.77 | PLAU (0.38) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |