Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 16/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779717 | 0.85 | BRAF (0.43) | BRAFRAF1CASR | |
| SCHEMBL4359613 | 0.79 | CYP1A2 (0.49) | LMNAL3MBTL1KMT2A | |
| SCHEMBL9063261 | 0.72 | LMNA (0.63) | LMNAL3MBTL1KMT2A | |
| SCHEMBL9857703 | 0.72 | LMNA (0.63) | LMNAL3MBTL1KMT2A | |
| SCHEMBL4353858 | 0.72 | CLK4 (0.59) | LMNAKMT2A | |
| SCHEMBL4575121 | 0.69 | EPHX2 (0.53) | LMNAL3MBTL1KMT2A | |
| SCHEMBL10730420 | 0.68 | L3MBTL1 (0.42) | LMNAL3MBTL1KMT2A | |
| SCHEMBL4351973 | 0.67 | LMNA (0.42) | LMNAL3MBTL1KMT2A | |
| SCHEMBL28798228 | 0.66 | PCSK9 (0.56) | CASR | |
| SCHEMBL11012644 | 0.66 | LMNA (0.70) | LMNAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009078-A2 | 4,6-DL- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | claimed |