Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779852 | 0.91 | KDM4E (0.48) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4783366 | 0.87 | RIPK1 (0.35) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4728992 | 0.85 | CNR1 (0.45) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4726236 | 0.84 | GABRA2 (0.47) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4729482 | 0.83 | SMN1; SMN2 (0.41) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL4728229 | 0.83 | KDM4E (0.47) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4729420 | 0.83 | CNR1 (0.46) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4727572 | 0.82 | CNR1 (0.49) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4876719 | 0.81 | KDM4E (0.45) | MEN1MAPTKMT2AKDM4EMAPK1 | |
| SCHEMBL4730476 | 0.80 | CNR1 (0.45) | MEN1MAPTKMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035356-A2 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |