Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.68 |
| ▸ | ERN1 | O75460 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12584704 | 0.80 | PTGS2 (0.50) | AKR1B1ERN1MAPTALOX5PTGS2 | |
| SCHEMBL4780375 | 0.78 | MAPT (0.64) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL16978279 | 0.78 | ERN1 (0.49) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL6131877 | 0.78 | ERN1 (0.49) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL27082323 | 0.77 | AKR1B1 (0.61) | AKR1B1MAPTALOX15EGFRPOLB | |
| SCHEMBL12767437 | 0.77 | ERN1 (1.00) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL31060309 | 0.77 | ERN1 (1.00) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL1620685 | 0.74 | ALOX5 (0.53) | AKR1B1ERN1MAPTNPSR1ALOX5 | |
| SCHEMBL1646879 | 0.74 | ERN1 (0.64) | ERN1MAPTTDP1KDM4ELMNA | |
| SCHEMBL1879373 | 0.73 | ERN1 (0.64) | ERN1MAPTALOX5PTGS2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871370-A2 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | Pinnacle Pharmaceuticals (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2007086895-A9 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007086895-A9 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007086895-A2 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007086895-A2 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-08-02 | — | — | WO | disclosed |
| US-20060235047-A1 | Antibacterial compounds and uses thereof | PINNACLE PHARMACEUTICALS | 2006-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235047-A1 | Antibacterial compounds and uses thereof | PBDC1, TRIB1, TRIB2 | AKR1B1 2412/4885ERN1 2969/4885MAPT 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.