Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728071 | 0.85 | USP1 (0.46) | CCNT1CDK2CDK7CDK9CCNC | |
| SCHEMBL4727785 | 0.84 | CCNT1 (0.46) | CCNT1CDK9MAPK1TRPV1CTSA | |
| SCHEMBL27738470 | 0.84 | NTRK1 (0.48) | CCNT1CDK2CDK9CCNCCDK8 | |
| SCHEMBL4777633 | 0.83 | CLK4 (0.41) | ROCK1ROCK2MAPK1P4HBLMNA | |
| SCHEMBL14670525 | 0.79 | NTRK1 (0.44) | CCNT1CDK2CDK7CDK9ROCK1 | |
| SCHEMBL14670408 | 0.79 | NTRK1 (0.44) | CCNT1CDK2CDK7CDK9ROCK1 | |
| SCHEMBL4729983 | 0.78 | PGR (0.45) | CCNT1CDK2CDK7CDK9CDK8 | |
| SCHEMBL4780125 | 0.78 | FAAH (0.51) | CCNT1 | |
| SCHEMBL4725583 | 0.77 | CCNT1 (0.41) | CCNT1CDK9ROCK2MAPK1TRPV1 | |
| SCHEMBL4727884 | 0.77 | AURKA (0.48) | CDK2CDK9ROCK1ROCK2CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |