Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781031 | 0.85 | GAA (0.40) | TP53LMNAMAPTTSHRALDH1A1 | |
| SCHEMBL4775240 | 0.84 | MEN1 (0.41) | BPTFLMNAMAPTTSHRALDH1A1 | |
| SCHEMBL4779333 | 0.82 | CHRM4 (0.39) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL4321609 | 0.80 | GRM5 (0.42) | ALDH1A1BACE1DPP4DPP8DPP9 | |
| SCHEMBL4774390 | 0.79 | KDM4E (0.40) | SLC6A3SMN1; SMN2RAB9AALDH1A1SLC6A2 | |
| SCHEMBL4780326 | 0.77 | CHRM4 (0.40) | SLC6A3SMN1; SMN2ALDH1A1SLC6A2DPP4 | |
| SCHEMBL4778369 | 0.76 | NOTUM (0.40) | TP53SMN1; SMN2LMNATSHRALDH1A1 | |
| SCHEMBL4780332 | 0.76 | CHRM4 (0.38) | SLC6A3TP53SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL4780839 | 0.76 | SLC6A2 (0.44) | LMNABACE1SLC6A2 | |
| SCHEMBL8168773 | 0.73 | FUCA1 (0.50) | ALDH1A1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |