Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 7/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321609 | 0.86 | GRM5 (0.42) | CHRM4RORCDPP4DRD2DRD3 | |
| SCHEMBL4778369 | 0.86 | NOTUM (0.40) | CHRM4DRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL4781178 | 0.84 | UBE2M (0.39) | RORCUBE2MDCUN1D1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4779787 | 0.84 | FFAR4 (0.38) | DPP4UBE2MDCUN1D1DPP8DPP9 | |
| SCHEMBL4776176 | 0.82 | FFAR4 (0.40) | SLC6A2SLC6A4SLC6A3UBE2MDCUN1D1 | |
| SCHEMBL4774338 | 0.82 | DRD2 (0.32) | CHRM4HTTRORCDPP4DRD2 | |
| SCHEMBL4775240 | 0.82 | MEN1 (0.41) | HTTRORCDPP4UBE2MDCUN1D1 | |
| SCHEMBL4780332 | 0.82 | CHRM4 (0.38) | CHRM4SLC6A3UBE2MDCUN1D1DRD2 | |
| SCHEMBL4779536 | 0.82 | DRD2 (0.32) | CHRM4HTTRORCDPP4DRD2 | |
| SCHEMBL4779333 | 0.81 | CHRM4 (0.39) | CHRM4DPP4UBE2MDCUN1D1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |