Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779333 | 0.88 | CHRM4 (0.39) | CHRM2CHRM1DPP4DPP8DPP9 | |
| SCHEMBL4781031 | 0.85 | GAA (0.40) | ALDH1A1RORCMAPTTSHRLMNA | |
| SCHEMBL4780315 | 0.84 | BPTF (0.43) | ALDH1A1DPP4DPP8DPP9DPP7 | |
| SCHEMBL4780326 | 0.82 | CHRM4 (0.40) | ALDH1A1HTTRORCDPP4DPP8 | |
| SCHEMBL4774390 | 0.79 | KDM4E (0.40) | MEN1KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL4778369 | 0.79 | NOTUM (0.40) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL4780839 | 0.78 | SLC6A2 (0.44) | CHRM2CHRM1SIGMAR1LMNA | |
| SCHEMBL4779536 | 0.78 | DRD2 (0.32) | ALDH1A1HTTRORCDPP4DPP8 | |
| SCHEMBL4774338 | 0.78 | DRD2 (0.32) | ALDH1A1HTTRORCDPP4DPP8 | |
| SCHEMBL4779787 | 0.78 | FFAR4 (0.38) | MEN1KMT2ADPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |