Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774183 | 0.86 | NPC1 (0.37) | SIGMAR1 | |
| SCHEMBL4781031 | 0.85 | GAA (0.40) | BCHEACHEBACE1LMNA | |
| SCHEMBL4776176 | 0.81 | FFAR4 (0.40) | SLC6A2SLC6A4BCHEACHEBACE1 | |
| SCHEMBL4776044 | 0.78 | RORC (0.41) | SLC6A2SLC6A4BCHE | |
| SCHEMBL4778295 | 0.78 | SIGMAR1 (0.46) | LMNASIGMAR1 | |
| SCHEMBL4781028 | 0.78 | KDM4E (0.43) | NOTUM | |
| SCHEMBL4775240 | 0.78 | MEN1 (0.41) | CHRM2LMNACHRM1SIGMAR1 | |
| SCHEMBL4779333 | 0.77 | CHRM4 (0.39) | CHRM4CHRM2CHRM1 | |
| SCHEMBL4780315 | 0.76 | BPTF (0.43) | SLC6A2BACE1LMNA | |
| SCHEMBL23578325 | 0.75 | BCHE (0.53) | SLC6A2SLC6A4BCHEACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010061-A2 | 3-AZABICYCLO [3.1.0] HEXANE VANILLOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-01-24 | — | — | WO | disclosed |