Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 1/20 | 0.42 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.38 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780443 | 0.87 | PDE5A (0.38) | KDM4EALDH1A1EPHX2ADORA1 | |
| SCHEMBL4776487 | 0.87 | PDE5A (0.38) | KDM4EALDH1A1EPHX2ADORA1 | |
| SCHEMBL4796379 | 0.87 | PDE5A (0.38) | KDM4EALDH1A1EPHX2ADORA1 | |
| SCHEMBL14303801 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL4778076 | 0.83 | PDE5A (0.40) | ALDH1A1MEN1HPGDKMT2AADORA1 | |
| SCHEMBL4774100 | 0.82 | NOS3 (0.42) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL4778365 | 0.81 | PDE5A (0.40) | ALDH1A1MEN1HPGDKMT2AEPHX2 | |
| SCHEMBL4778323 | 0.81 | NOS3 (0.43) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL14303430 | 0.79 | PDE5A (0.40) | ALDH1A1MEN1HPGDKMT2AADORA1 | |
| SCHEMBL4780605 | 0.77 | BRAF (0.38) | KDM4EALDH1A1MAPTHPGDMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |