Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778137 | 0.89 | ALDH1A1 (0.48) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4774577 | 0.82 | CNR2 (0.51) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4775577 | 0.79 | POLB (0.46) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4778107 | 0.79 | LTB4R (0.48) | MEN1MAPTKMT2APOLBCYP19A1 | |
| SCHEMBL4778315 | 0.77 | POLB (0.44) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4774514 | 0.70 | ALDH1A1 (0.47) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4780661 | 0.70 | ABCG2 (0.51) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL4812078 | 0.69 | CNR2 (0.50) | ALDH1A1MEN1MAPTKMT2APOLB | |
| SCHEMBL29466702 | 0.69 | TSHR (0.57) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL15562841 | 0.69 | TSHR (0.57) | ALDH1A1MEN1MAPTKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008009963-A2 | PYRIMIDINE DERIVATIVES AS MODULATORS OF PARATHYROID HORMONE RECEPTORS | JAMES BLACK FOUNDATION LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |