Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339492 | 0.85 | ALOX15 (0.81) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL14546296 | 0.82 | MEN1 (0.47) | TBXAS1MEN1MAPTKMT2A | |
| SCHEMBL13772574 | 0.82 | MAOB (0.44) | ALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL166364 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL9832704 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL2642068 | 0.82 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL8373906 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL1249954 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL10399496 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1TBXAS1 | |
| SCHEMBL2336059 | 0.80 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008480-A2 | NITROHETEROARYL-CONTAINING RIFAMYCIN DERIVATIVES | CUMBRE PHARMACEUTICALS INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| US-5180730-A | Pyridylthiomethyl-Substituted Phenols, Antianaphylactic Agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-4965260-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1990-10-23 | — | — | US | disclosed |
| US-4933348-A | MEDICINES; ANTAGONISTS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS; PROPHYLAXIS AND TREATMENT OF ALLERGIC DISEASES | MASE TOSHIYASU (JP) | 1990-06-12 | — | — | US | disclosed |
| US-4803211-A | Thiadizazole compounds as antagonists of SRS-A | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0278911-A1 | Bicyclic beta-lactam carboxylic acids | CIBA-GEIGY AG (CH) | 1988-08-17 | — | — | EP | disclosed |
| EP-0214732-A2 | (Substituted benzyl)-thio heterocyclic compounds having a leukotriene-antagonist activity | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-03-18 | — | — | EP | disclosed |
| US-4461905-A | THROMBOXANE SYNTHETASE INHIBITOR INTERMEDIATE | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |