SCHEMBL9832704

SCHEMBL9832704

O=C(O)COc1ccc(CC(=O)O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.63
PLA2G4B P0C869 1/20 0.59
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
FFAR1 O14842 1/20 0.56
PTPN7 P35236 2/20 0.55
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
PTPN12 Q05209 1/20 0.55
CA2 P00918 1/20 0.54
CAMK2A Q9UQM7 1/20 0.54
AKR1B1 P15121 1/20 0.52
TSHR P16473 2/20 0.51
SRD5A2 P31213 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NR4A1 P22736 1/20 0.51
APEX1 P27695 1/20 0.51
PPARG P37231 1/20 0.51
PPARD Q03181 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL2343498 0.88 ALOX15 (0.77) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL339492 0.87 ALOX15 (0.81) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL27869587 0.86 ALOX15 (0.57) ALOX15PLA2G4BALDH1A1SMN1; SMN2FFAR1
SCHEMBL14939906 0.86 ALOX15 (0.57) ALOX15PLA2G4BALDH1A1SMN1; SMN2FFAR1
SCHEMBL10702374 0.86 ALOX15 (0.57) ALOX15PLA2G4BALDH1A1SMN1; SMN2FFAR1
SCHEMBL23582938 0.86 PLA2G4B (0.55) ALOX15PLA2G4BMEN1MAPTKMT2A
SCHEMBL23582957 0.86 ALOX15 (0.57) ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7
SCHEMBL11210089 0.86 ALOX15 (0.57) ALOX15PLA2G4BALDH1A1SMN1; SMN2FFAR1
SCHEMBL11683055 0.85 PLA2G4B (0.61) ALOX15PLA2G4BALDH1A1SMN1; SMN2FFAR1
Phenylacetic Acid SCHEMBL7800635 0.84 ALOX15 (0.59) ALOX15ALDH1A1FFAR1PTPN7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-7161010-B2 Methine dyes; coloring compound FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
US-20070004923-A1 Methine compound and silver halide photographic material containing the same FUJI PHOTO FILM CO., LTD. 2007-01-04 US disclosed
CN-1120334-A Heterocyclic derivatives as platelet aggregation inhibitors ZENECA LTD (GB) 1996-04-10 CN disclosed
EP-0406127-A1 Polyamides with improved gas barrier properties EASTMAN KODAK COMPANY (US) 1991-01-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004923-A1 Methine compound and silver halide photographic material containing the same PYM1, NPM1, METTL3 ALOX15 2821/4885PLA2G4B 4776/4885ALDH1A1 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.